IGF-1 LR3 1mg China Supplier

Buy IGF-1 LR3 1mg from China Supplier

Igf-1 long r3 is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF-1 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus. This makes Long R3 IGF-I significantly more potent (2-3x) than IGF-I in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins, and consequently more potential activity in the body.

1 Kit = 10 Vials of 1mg/Vial

IGF-1 plays a crucial role in muscle regeneration. IGF-1 stimulates both proliferation and differentiation of stem cells in an autocrine-paracrine manner, although it induces differentiation to a much greater degree.

IGF-1, when injected locally, increases satellite cell activity, muscle DNA, muscle protein content, muscle weight and muscle cross sectional area. The importance of IGF-1 lies in the fact that all of its apparent functions act to induce muscle growth with or without overload although it really shines as a growth promoter when combined with physical loading of the muscle.

IGF-1 also acts as an endocrine growth factor having an anabolic effect on distant tissues once released into the blood stream by the liver. IGF-1 possesses the insulin-like property of inhibiting degradation, but in addition can stimulate protein synthesis. The insulin-like effects are probably due to the similarity of the signaling pathways between insulin and IGF-1 following ligand binding at the receptors.

The ability of IGF-I to stimulate protein synthesis resembles the action of GH, which was shown in separate studies on volunteers to stimulate protein synthesis without affecting protein degradation. Although it is often believed that the effects of GH are mediated through IGF-1, this cannot be the case entirely. First, the effects of the two hormones are different, in that GH does not change protein degradation. Second, the effect of GH is observed with little or no change in systemic IGF-1 concentrations.

Product Details:

Product Name: IGF-1 LR3
Package: 1mg/vial, 10 vials/box
Molecular Formula: C400H625N111O115S9
Purity: 98.0% min.
Appearance: White powder
Certification: GMP, SFDA

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Delivery & Shipping Terms:

1. We will ship the goods within 1 days after receiving the payment.
2. International orders are shipped by UPS, EMS, DHL, TNT or FEDEX. We will choose the best courier depending on different countries, and find the safest way to deliver the goods for you.
3. Domestic orders are shipped using national postal system.
4. Delivery time EMS: 5-14 days. DHL/UPS/FedEx: 4-7 days.
5. If the goods were lost or not received for other reasons, we'll resend on our expenses.